Pistol
The pistol is a nice little weapon, and it'll serve you well on the weaker splicers that you come across, especially when dealing with Leadhed Splicers early on in the game. As you progress in the game, the damage output probably won't be enough to keep up with the increasing health of your enemies (unless you can make a lot of anti-personnel ammo at the U-Invent), but you can still use the pistol as a rapid method of hitting explosives that are near your opponents, or to quickly eliminate turrets with anti-armor ammunition.
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